PLAT MaxPab rabbit polyclonal antibody (D01)
产品名称： PLAT MaxPab rabbit polyclonal antibody (D01)
英文名称： PLAT MaxPab rabbit polyclonal antibody (D01)
产品编号： H00005327-D01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human PLAT protein.
- Immunogen:
- PLAT (NP_000921.1, 1 a.a. ~ 562 a.a) full-length human protein.
- Sequence:
- MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of PLAT expression in transfected 293T cell line (H00005327-T01) by PLAT MaxPab polyclonal antibody.
Lane 1: PLAT transfected lysate(62.90 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunoprecipitation
- Immunoprecipitation of PLAT transfected lysate using anti-PLAT MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PLAT MaxPab mouse polyclonal antibody (B01) (H00005327-B01).
- Protocol Download
- Entrez GeneID:
- 5327
- GeneBank Accession#:
- NM_000930.2
- Protein Accession#:
- NP_000921.1
- Gene Name:
- PLAT
- Gene Alias:
- DKFZp686I03148,T-PA,TPA
- Gene Description:
- plasminogen activator, tissue
- Omim ID:
- 173370
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- alteplase,plasminogen activator, tissue type,reteplase,t-plasminogen activator,tissue plasminogen activator (t-PA)
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Aneurysm, Ruptured
- Arterial Occlusive Diseases
- Arteriosclerosis
- Arthritis, Rheumatoid
- Atherosclerosis
- Atherosclerosis
- Brain Infarction
- Brain Ischemia
- Calcinosis
- Cardiovascular Diseases
- Cerebral Palsy
- Cerebrovascular Accident
- Chorioamnionitis
- Connective Tissue Diseases
- Coronary Artery Disease
- Coronary Disease