Anti-EIF4G2 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K000375P-50ul	solarbio	50ul	960.00元
K000375P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-EIF4G2 Polyclonal Antibody
别名	AAG1;DAP5;NAT1;P97
应用	WB IHC
稀释比例	WB 1:500-1000. IHC 1:100-200.
交叉反应	Human Mouse Rat
蛋白分子量	102kDa
Gene ID	1982
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human EIF4G2
性状	液体
Public Immunogen Range	A synthetic peptide of human EIF4G2
Subcellular Locations	Cytosol
Swiss Prot	P78344
克隆类型	Polyclonal Antibody
背景资料	Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.